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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNK2
All Species:
3.94
Human Site:
T2173
Identified Species:
10.83
UniProt:
Q9Y3S1
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3S1
NP_006639.3
2297
242676
T2173
V
D
E
W
T
S
K
T
V
G
A
A
Q
L
K
Chimpanzee
Pan troglodytes
XP_001150671
2354
247864
A2233
V
D
N
W
A
R
D
A
M
N
L
S
G
R
R
Rhesus Macaque
Macaca mulatta
XP_001108626
2142
225829
N2030
L
H
V
Q
A
Q
V
N
N
S
N
N
K
K
G
Dog
Lupus familis
XP_853960
2389
250985
A2268
V
D
N
W
A
R
D
A
M
N
L
S
G
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH66
2149
227509
E2036
S
S
L
A
P
G
P
E
P
G
P
Q
P
T
L
Rat
Rattus norvegicus
Q9JIH7
2126
225198
A2005
V
D
N
W
A
R
D
A
M
N
L
S
G
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508024
2425
260713
T2278
V
D
E
W
T
I
K
T
V
G
S
T
Q
L
K
Chicken
Gallus gallus
XP_414326
2183
235443
R2054
S
I
W
S
T
L
K
R
L
C
L
G
K
D
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001344215
2001
216452
V1889
D
N
W
A
E
G
Y
V
L
T
D
W
L
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.7
86.9
29.1
N.A.
76
29.7
N.A.
55
54.5
N.A.
38.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
43
87.9
42.4
N.A.
79.9
43.4
N.A.
64.4
63.6
N.A.
50.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
0
20
N.A.
6.6
20
N.A.
80
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
13.3
40
N.A.
6.6
40
N.A.
86.6
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
23
45
0
0
34
0
0
12
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
12
56
0
0
0
0
34
0
0
0
12
0
0
12
0
% D
% Glu:
0
0
23
0
12
0
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
23
0
0
0
34
0
12
34
0
12
% G
% His:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
34
0
0
0
0
0
23
12
23
% K
% Leu:
12
0
12
0
0
12
0
0
23
0
45
0
12
23
12
% L
% Met:
0
0
0
0
0
0
0
0
34
0
0
0
0
12
0
% M
% Asn:
0
12
34
0
0
0
0
12
12
34
12
12
0
0
0
% N
% Pro:
0
0
0
0
12
0
12
0
12
0
12
0
12
0
0
% P
% Gln:
0
0
0
12
0
12
0
0
0
0
0
12
23
0
0
% Q
% Arg:
0
0
0
0
0
34
0
12
0
0
0
0
0
34
45
% R
% Ser:
23
12
0
12
0
12
0
0
0
12
12
34
0
0
0
% S
% Thr:
0
0
0
0
34
0
0
23
0
12
0
12
0
12
0
% T
% Val:
56
0
12
0
0
0
12
12
23
0
0
0
0
0
0
% V
% Trp:
0
0
23
56
0
0
0
0
0
0
0
12
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _